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Dr Abrahams Study


The Dr. Guy Abraham Study of 1990

The resuts of this study suggests that 500 mg of Calcium & 600 mg of Magnesium has a significant effect on reversing postmenopausal bone loss within a relatively short period of time. The effect of this magnesium-empthasized program on bone density was 16 times greater than that of dietary advice alone. There was a 11% increase in bone density using 500 mg Calcium & 600 mg Magnesium. (Table II)

Vol. 35 No. 5, May 1990

A Total Dietary Program Emphasizing Magnesium Instead of Calcium.

Effect on the Mineral Density of Calcaneous Bone in Postmenopausal Women on Hormonal Therapy

Guy E. Abraham, / M.D. Harinder Grewal, M.D.

The use of calcium supplementation for the management of primary postmenopausal osteoporosis (PPMO) has increased significantly in the past few years. A review of the published data does not support calcium mega dosing during post menopause. Controlled studies showed no significant effect of calcium intake on mineral density of trabecular bone and a slight effect on cortical bone.

Since PPMO is predominantly due to demineralization of trabecular bone, there is no justification for calcium mega dosing in postmenopausal women. Soft tissue calcification is a serious risk factor during calcium mega dosing under certain conditions. A total dietary program emphasizing magnesium instead of calcium for the management of PPMO takes into account the available data on the effects of magnesium, life-style and dietary habits on bone integrity and PPMO.

When this dietary program was tested on 19 postmenopausal women on hormonal replacement therapy who were compared to 7 control postmenopausal women, a significant increase in mineral bone density of the calcaneous bone (BMD) was observed within one year. Fifteen of the 19 women had had BMD below the spinefracture threshold before treatment; within one year, only 7 of them still had BMD values below that threshold.